Moldofsky Harvey
Sleep Disorders Clinics of the Centre for Sleep & Chronobiology, University of Toronto, Toronto, Ontario, Canada.
Rheum Dis Clin North Am. 2009 May;35(2):275-83. doi: 10.1016/j.rdc.2009.05.008.
This article reviews how functional disturbances of the sleeping-waking brain are involved in pathogenesis of the widespread pain, unrefreshing sleep, fatigue, and impaired quality of life of patients who have fibromyalgia syndrome. Recent studies of the effects on EEG sleep by some specific pharmacologic and physical therapeutic agents demonstrate not only benefit for the widespread pain and fatigue, but also improved sleep physiology and restorative sleep of patients who suffer from fibromyalgia.
本文综述了睡眠-觉醒大脑的功能紊乱如何参与纤维肌痛综合征患者广泛疼痛、睡眠不佳、疲劳及生活质量受损的发病机制。近期关于某些特定药物和物理治疗剂对脑电图睡眠影响的研究表明，这些治疗不仅对广泛疼痛和疲劳有益，还能改善纤维肌痛患者的睡眠生理及恢复性睡眠。
