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超越纤维肌痛:关于病因与治疗的见解

Beyond fibromyalgia: ideas on etiology and treatment.

作者信息

Bennett R M

机构信息

Division of Arthritis and Rheumatic Diseases, Oregon Health Sciences University, Portland 97201.

出版信息

J Rheumatol Suppl. 1989 Nov;19:185-91.

PMID:2691678
Abstract

A common syndrome of musculoskeletal pain, currently called fibrositis or fibromyalgia, accounts for 10-30% of all rheumatology consultations in North America. Lacking a distinctive pathophysiological basis the nature of the pain experienced by these patients remains elusive and treatment is not based on sound scientific principles. An hypothesis is advanced which suggests that skeletal muscle is the "end organ" responsible for the pain of fibromyalgia and that previous studies on muscle deconditioning and microtrauma may be relevant to the etiopathogenesis of fibromyalgia syndrome.

摘要

一种常见的肌肉骨骼疼痛综合征,目前称为纤维织炎或纤维肌痛,在北美所有风湿病会诊病例中占10%至30%。由于缺乏独特的病理生理基础,这些患者所经历疼痛的本质仍然难以捉摸,而且治疗并非基于可靠的科学原则。本文提出一种假说,认为骨骼肌是纤维肌痛疼痛的“终末器官”,并且先前关于肌肉失健和微创伤的研究可能与纤维肌痛综合征的病因发病机制相关。

相似文献

1
Beyond fibromyalgia: ideas on etiology and treatment.超越纤维肌痛:关于病因与治疗的见解
J Rheumatol Suppl. 1989 Nov;19:185-91.
2
The significance of dysfunctions of the sleeping/waking brain to the pathogenesis and treatment of fibromyalgia syndrome.睡眠/觉醒大脑功能障碍对纤维肌痛综合征发病机制及治疗的意义。
Rheum Dis Clin North Am. 2009 May;35(2):275-83. doi: 10.1016/j.rdc.2009.05.008.
3
Sleep related myoclonus in rheumatic pain modulation disorder (fibrositis syndrome).风湿性疼痛调节障碍(纤维肌痛综合征)中的睡眠相关性肌阵挛。
J Rheumatol. 1986 Jun;13(3):614-7.
4
Sleep and symptoms in fibrositis syndrome after a febrile illness.
J Rheumatol. 1988 Nov;15(11):1701-4.
5
Fibromyalgia syndrome: review of clinical presentation, pathogenesis, outcome measures, and treatment.纤维肌痛综合征:临床表现、发病机制、结局指标及治疗综述
J Rheumatol Suppl. 2005 Aug;75:6-21.
6
Nonrestorative sleep and symptoms after a febrile illness in patients with fibrositis and chronic fatigue syndromes.纤维炎和慢性疲劳综合征患者发热性疾病后的睡眠恢复不佳及症状
J Rheumatol Suppl. 1989 Nov;19:150-3.
7
Primary fibromyalgia is greater than tender points: toward a multiaxial taxonomy.
J Rheumatol Suppl. 1989 Nov;19:80-6.
8
Fibromyalgia: knowns, unknowns, and current treatment.纤维肌痛:已知、未知与当前治疗
Bull NYU Hosp Jt Dis. 2010;68(3):157-61.
9
[The diagnosis and treatment of fibromyalgia].[纤维肌痛的诊断与治疗]
Acta Med Port. 1995 Apr;8(4):233-8.
10
Fibromyalgia: state of the art.纤维肌痛:最新进展
Minerva Med. 2004 Feb;95(1):35-47, 47-52.

引用本文的文献

1
GH/IGF1 axis disturbances in the fibromyalgia syndrome: is there a rationale for GH treatment?纤维肌痛综合征中的生长激素/胰岛素样生长因子-1轴紊乱:生长激素治疗是否有理论依据?
Pituitary. 2014 Jun;17(3):277-83. doi: 10.1007/s11102-013-0486-0.
2
Relationship between sleep and pain in adolescents with juvenile primary fibromyalgia syndrome.青少年原发性纤维肌痛综合征睡眠与疼痛的关系。
Sleep. 2013 Apr 1;36(4):509-16. doi: 10.5665/sleep.2534.
3
Central pain mechanisms in chronic pain states--maybe it is all in their head.慢性疼痛状态中的中枢疼痛机制——也许这一切都在他们的头脑中。
Best Pract Res Clin Rheumatol. 2011 Apr;25(2):141-54. doi: 10.1016/j.berh.2011.02.005.
4
A comprehensive study of autonomic dysfunction in the fibromyalgia patients.对纤维肌痛患者自主神经功能障碍的综合研究。
Clin Auton Res. 2012 Jun;22(3):117-22. doi: 10.1007/s10286-011-0150-6. Epub 2011 Oct 25.
5
Serum growth hormone and insulin but not insulin-like growth factor-1 levels are elevated in patients with fibromyalgia syndrome.纤维肌痛综合征患者的血清生长激素和胰岛素水平升高,但胰岛素样生长因子-1水平未升高。
Rheumatol Int. 2005 Mar;25(2):146-51. doi: 10.1007/s00296-004-0459-8. Epub 2004 Jul 24.
6
Psychological stress and fibromyalgia: a review of the evidence suggesting a neuroendocrine link.心理压力与纤维肌痛:关于神经内分泌联系的证据综述
Arthritis Res Ther. 2004;6(3):98-106. doi: 10.1186/ar1176. Epub 2004 Apr 7.
7
Adult growth hormone deficiency in patients with fibromyalgia.纤维肌痛患者的成人生长激素缺乏症。
Curr Rheumatol Rep. 2002 Aug;4(4):306-12. doi: 10.1007/s11926-002-0039-4.