Bennett R M
Division of Arthritis and Rheumatic Diseases, Oregon Health Sciences University, Portland 97201.
J Rheumatol Suppl. 1989 Nov;19:185-91.
A common syndrome of musculoskeletal pain, currently called fibrositis or fibromyalgia, accounts for 10-30% of all rheumatology consultations in North America. Lacking a distinctive pathophysiological basis the nature of the pain experienced by these patients remains elusive and treatment is not based on sound scientific principles. An hypothesis is advanced which suggests that skeletal muscle is the "end organ" responsible for the pain of fibromyalgia and that previous studies on muscle deconditioning and microtrauma may be relevant to the etiopathogenesis of fibromyalgia syndrome.
一种常见的肌肉骨骼疼痛综合征,目前称为纤维织炎或纤维肌痛,在北美所有风湿病会诊病例中占10%至30%。由于缺乏独特的病理生理基础,这些患者所经历疼痛的本质仍然难以捉摸,而且治疗并非基于可靠的科学原则。本文提出一种假说,认为骨骼肌是纤维肌痛疼痛的“终末器官”,并且先前关于肌肉失健和微创伤的研究可能与纤维肌痛综合征的病因发病机制相关。