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No association of the rs4646396 SNP in the PEMT locus with schizophrenia in a Chinese case-control sample.

作者信息

Li Heyao, Zhang Haiying, Liu Libo, Ju Guizhi, Jin Shunzi, Ye Lin, Zhang Xuan, Wei Jun

机构信息

Research Center for Neuroscience & MH Radiobiology Research Unit, School of Public Health, Jilin University, Changchun 130021, China.

出版信息

Psychiatry Res. 2009 Sep 30;169(2):176-7. doi: 10.1016/j.psychres.2008.11.004. Epub 2009 Aug 3.

DOI:10.1016/j.psychres.2008.11.004
PMID:19647326
Abstract

The present study included a total of 628 patients with schizophrenia and 588 healthy controls to replicate the genetic association between the PEMT gene and schizophreia. However, our results in this study failed to confirm our earlier finding that the C allele was preferentially transmitted by parents to their offspring affected with schizophrenia in a family-based study among the Chinese population.

摘要

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