Carter P E, McTavish S M, Brooks H J L, Campbell D, Collins-Emerson J M, Midwinter A C, French N P
ESR Ltd, Porirua, New Zealand.
Appl Environ Microbiol. 2009 Oct;75(19):6038-46. doi: 10.1128/AEM.01039-09. Epub 2009 Jul 31.
Campylobacter jejuni is widely distributed in the environment, and river water has been shown to carry high levels of the organism. In this study, 244 C. jejuni isolates from three river catchment areas in New Zealand were characterized using multilocus sequence typing. Forty-nine of the 88 sequence types identified were new. The most common sequence types identified were ST-2381 (30 isolates), ST-45 (25 isolates), and ST-1225 (23 isolates). The majority of the sequence types identified in the river water could be attributed to wild bird fecal contamination. Two novel clonal complexes (CC) were identified, namely, CC ST-2381 (11 sequence types, 46 isolates) and CC ST-3640 (6 sequence types, 12 isolates), in which all of the sequence types were new. CC ST-2381 was the largest complex identified among the isolates and was present in two of the three rivers. None of the sequence types associated with the novel complexes has been identified among human isolates. The ST-2381 complex is not related to complexes associated with cattle, sheep, or poultry. The source of the novel complexes has yet to be identified.
空肠弯曲菌广泛分布于环境中，河水已被证明携带大量该菌。在本研究中，使用多位点序列分型对来自新西兰三个河流集水区的244株空肠弯曲菌分离株进行了特征分析。在鉴定出的88种序列类型中，有49种是新的。鉴定出的最常见序列类型为ST-2381（30株分离株）、ST-45（25株分离株）和ST-1225（23株分离株）。河水中鉴定出的大多数序列类型可归因于野生鸟类粪便污染。鉴定出两个新的克隆复合体（CC），即CC ST-2381（11种序列类型，46株分离株）和CC ST-3640（6种序列类型，12株分离株），其中所有序列类型都是新的。CC ST-2381是分离株中鉴定出的最大复合体，存在于三条河流中的两条。在人类分离株中未鉴定出与新复合体相关的任何序列类型。ST-2381复合体与牛、羊或家禽相关的复合体无关。新复合体的来源尚未确定。
