Gillings Michael R, Labbate Maurizio, Sajjad Ammara, Giguère Nellie J, Holley Marita P, Stokes H W
Department of Biological Sciences, Macquarie University, Sydney, NSW 2109, Australia.
Appl Environ Microbiol. 2009 Sep;75(18):6002-4. doi: 10.1128/AEM.01033-09. Epub 2009 Jul 31.
A Tn402-like class 1 integron was recovered from a prawn-associated bacterium. One of its cassettes included methionine sulfoxide reductase genes, the first example of such genes being captured by an integron. The integron was flanked by direct repeats that resemble miniature inverted-repeat transposable element sequences. Excision of the integron by homologous recombination through these sequences was demonstrated.
从一种与对虾相关的细菌中发现了一个类似Tn402的1类整合子。其一个盒式结构包含甲硫氨酸亚砜还原酶基因,这是此类基因被整合子捕获的首个实例。该整合子两侧是类似微型反向重复转座元件序列的正向重复序列。通过这些序列进行同源重组实现整合子切除得到了证实。