Program in Cellular, Molecular and Microbial Biology, Division of Biological Sciences, University of Montana, Missoula, MT 59812, USA.
Genes (Basel). 2024 Mar 3;15(3):328. doi: 10.3390/genes15030328.
Prokaryotic genomes are dynamic tapestries that are strongly influenced by mobile genetic elements (MGEs), including transposons (Tn's), plasmids, and bacteriophages. Of these, miniature inverted-repeat transposable elements (MITEs) are undoubtedly the least studied MGEs in bacteria and archaea. This review explores the diversity and distribution of MITEs in prokaryotes and describes what is known about their functional roles in the host and involvement in genomic plasticity and evolution.
原核基因组是动态的挂毯,强烈受到移动遗传元件(MGEs)的影响,包括转座子(Tn's)、质粒和噬菌体。在这些元件中,微型反向重复转座元件(MITEs)无疑是细菌和古菌中研究最少的 MGEs。本综述探讨了 MITEs 在原核生物中的多样性和分布,并描述了它们在宿主中的功能作用以及在基因组可塑性和进化中的参与情况。