Adam P, Sobek O, Hybel'ová M, Dolezil D, Kasík J, Hajduková L, Adam D, Svatonová J
Laboratory for CSF and Neuroimmunology, Central Military Hospital Complex, Prague, Czech Republic.
Folia Microbiol (Praha). 2009;54(3):257-60. doi: 10.1007/s12223-009-0040-7. Epub 2009 Aug 2.
A very rare clinical entity, so-called eosinophilic meningitis, classified by prevalence of eosinophils in cerebrospinal fluid (CSF), with the presence of pleiocytosis, has been recorded in our laboratory four times only in the last 24 years. A low glucose level, elevation of total protein and lactic acid in CSF were detected in all the clinical cases. The last two cases were made possible by using flow cytometry method; surprisingly, the presence was found in mature T-cells in CSF, predominantly helpers (CD3+, CD4+) and, practically, none is B-cells (CD19+), plasma cells (CD138+) and NK-cells.
一种非常罕见的临床病症，即所谓的嗜酸性粒细胞性脑膜炎，根据脑脊液（CSF）中嗜酸性粒细胞的比例进行分类，伴有细胞增多现象，在我们实验室过去24年中仅记录到4次。在所有临床病例中均检测到脑脊液中葡萄糖水平降低、总蛋白和乳酸升高。最后两例是通过流式细胞术检测出来的；令人惊讶的是，在脑脊液的成熟T细胞中发现了这种情况，主要是辅助性T细胞（CD3 +、CD4 +），实际上几乎没有B细胞（CD19 +）、浆细胞（CD138 +）和NK细胞。
