Cohen Todd A, Nelson Richard W, Kass Philip H, Christopher Mary M, Feldman Edward C
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.
J Am Vet Med Assoc. 2009 Aug 1;235(3):276-80. doi: 10.2460/javma.235.3.276.
To evaluate accuracy of 6 portable blood glucose meters (PBGMs) by comparing results of these meters with results obtained with a reference chemistry analyzer.
Evaluation study.
49 dogs (158 blood samples). Procedures-Venous blood samples were tested with the 6 PBGMs, and results were compared with results of a commercially available analyzer that used a reference method based on the hexokinase reaction.
Plasma glucose concentrations obtained with the reference analyzer ranged from 41 to 639 mg/dL. There were significant correlations between blood glucose concentrations obtained with the 6 PBGMs and plasma glucose concentrations obtained with the reference analyzer (r > or = 0.96). However, for all 6 PBGMs, results differed from results for the reference analyzer, with the difference increasing as plasma glucose concentration increased. Significant differences in bias were found among meters. For 142 samples classified as hypoglycemic, euglycemic, or hyperglycemic on the basis of results of the reference analyzer, the percentage of samples that were misclassified on the basis of results of the PBGMs ranged from 2.1% to 38.7%.
Results of the present study suggested that there were substantial differences in the accuracy of currently available PBGMs when used to determine blood glucose concentration in dogs.
通过将6种便携式血糖仪（PBGMs）的检测结果与参考化学分析仪的检测结果进行比较，评估这些血糖仪的准确性。
评估研究。
49只犬（158份血样）。方法——用6种PBGMs检测静脉血样，并将结果与使用基于己糖激酶反应的参考方法的市售分析仪的结果进行比较。
参考分析仪测得的血浆葡萄糖浓度范围为41至639mg/dL。6种PBGMs测得的血糖浓度与参考分析仪测得的血浆葡萄糖浓度之间存在显著相关性（r≥0.96）。然而，对于所有6种PBGMs，其结果与参考分析仪的结果不同，且随着血浆葡萄糖浓度的增加，差异增大。各血糖仪之间的偏差存在显著差异。对于根据参考分析仪结果分类为低血糖、血糖正常或高血糖的142份样本，基于PBGMs结果误分类的样本百分比范围为2.1%至38.7%。
本研究结果表明，目前可用的PBGMs在用于测定犬血糖浓度时，准确性存在很大差异。
