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热疗对体外实验性病毒感染的影响。

Influence of hyperthermia on experimental viral infections in vitro.

作者信息

Panasiak W, Oraczewska A, Luczak M

机构信息

Department of Virology, Institute of Biostructure Medical Academy, Warsaw, Poland.

出版信息

Adv Exp Med Biol. 1990;267:471-5. doi: 10.1007/978-1-4684-5766-7_50.

Abstract

The effects of hyperthermia (39 and 41 C) on virus multiplication in vitro (HSV-1, VSV on Vero cells and EMC on L929 cells) have been explored. The cells were infected with HSV-1, VSV or EMC viruses and heated to 39 or 41 C before, during or after the viral infection. The titer of the virus show that temperature of 41 C acts as an inhibitory agent on HSV-1 and VSV virus replication in Vero cells.

摘要

已经探究了热疗(39℃和41℃)对体外病毒增殖的影响(单纯疱疹病毒1型、水泡性口炎病毒在非洲绿猴肾细胞上,脑心肌炎病毒在小鼠成纤维细胞L929上)。细胞用单纯疱疹病毒1型、水泡性口炎病毒或脑心肌炎病毒感染,并在病毒感染之前、期间或之后加热到39℃或41℃。病毒滴度表明41℃的温度对非洲绿猴肾细胞中单纯疱疹病毒1型和水泡性口炎病毒的复制起到抑制作用。

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