Singh G D, Ganjoo M, Youssouf M S, Koul A, Sharma R, Singh S, Sangwan P L, Koul S, Ahamad D B, Johri R K
Division of Pharmacology, Indian Institute of Integrative Medicine, Jammu 180001, India.
Food Chem Toxicol. 2009 Oct;47(10):2661-5. doi: 10.1016/j.fct.2009.07.031. Epub 2009 Aug 3.
Labisia pumila (Myrsinaceae), is a popular herb among the women in Malaysia known locally as "Kacip Fatimah". Recently many nutraceutical products containing the powdered or extracted parts of the plant have become available for women's health care. However no evaluation of the effect of the repeated dosing of any herbal product of this plant had been undertaken prior to a 28-day sub-acute study presented in this report. The results showed that a dose of 50mg/kg of an aqueous extract of L. pumila corresponded to no-adverse-effect-level (NOAEL), whereas higher doses were associated with some toxicity concerns.
矮陀陀（紫金牛科），是马来西亚女性中广受欢迎的一种草药，当地称为“卡奇普·法蒂玛”。最近，许多含有该植物粉末或提取物的营养保健品已用于女性保健。然而，在本报告中呈现的一项为期28天的亚急性研究之前，尚未对该植物任何草药产品的重复给药效果进行评估。结果表明，50mg/kg剂量的矮陀陀水提取物相当于无不良反应水平（NOAEL），而更高剂量则存在一些毒性问题。
