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腹腔镜辅助子宫肌瘤剔除术与开腹子宫肌瘤剔除术的短期结局比较:一项前瞻性研究。

Laparoscopically assisted myomectomy versus abdominal myomectomy in short-term outcomes: a prospective study.

机构信息

IAKENTRO, Advanced Medical Center, 4 A. Svolou Street, 54622, Thessaloniki, Greece.

出版信息

Arch Gynecol Obstet. 2010 May;281(5):865-70. doi: 10.1007/s00404-009-1187-9. Epub 2009 Aug 5.

Abstract

PURPOSE

Comparison between laparoscopically assisted myomectomy (LAM) and abdominal myomectomy (laparotomy), used in the management of women with intramural or subserous uterine fibroids up to 90 mm of maximum diameter.

METHODS

Seventy-five premenopausal women were prospectively enrolled in the study, managed by LAM (n=48) or by laparotomy (n=27) approach. The short-term outcomes were compared between the two groups. The patient characteristics were also analyzed.

RESULTS

The mean (+/-SD) estimated blood loss was significantly less in the LAM procedure compared with laparotomy (246+/-161 vs. 351+/-219 ml, respectively, P=0.03). Similarly, the operative time was shorter in the LAM modality compared with laparotomy (68+/-21 vs. 83+/-24 min, respectively, P=0.01). Intraoperative and postoperative complications were not different between the two groups. The mean days of the bowel reactivity (1.04+/-0.2) was faster (P<0.0001), while the duration of hospitalization (1.2+/-0.6) was shorter (P<0.0001) in the LAM technique, when compared with abdominal myomectomy (1.8+/-0.5 and 4.2+/-0.8, respectively).

CONCLUSIONS

In selected group of patients, LAM as minimally invasive approach is an attractive alternative to conventional laparotomic myomectomy, offering significant advantages.

摘要

目的

比较腹腔镜辅助子宫肌瘤剔除术(LAM)与剖腹子宫肌瘤剔除术(开腹)用于治疗最大直径达 90mm 的壁间或浆膜下子宫肌瘤的效果。

方法

75 例绝经前妇女前瞻性纳入本研究,分别接受 LAM(n=48)或剖腹手术(n=27)治疗。比较两组的短期结果。还分析了患者特征。

结果

与剖腹手术相比,LAM 术中估计出血量明显较少(分别为 246+/-161 与 351+/-219ml,P=0.03)。同样,LAM 手术的手术时间也短于剖腹手术(分别为 68+/-21 与 83+/-24min,P=0.01)。两组术中及术后并发症无差异。LAM 组肠道反应时间(1.04+/-0.2 天)更快(P<0.0001),而住院时间(1.2+/-0.6 天)更短(P<0.0001),与剖腹手术相比(分别为 1.8+/-0.5 天和 4.2+/-0.8 天)。

结论

在选择的患者群体中,LAM 作为微创方法是传统剖腹子宫肌瘤剔除术的一种有吸引力的替代方法,具有显著优势。

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