Struthers Parkinson's Center, Park Nicollet Health Services, 6701 Country Club Drive, Golden Valley,MI 55427, USA.
J Sex Med. 2010 Apr;7(4 Pt 1):1438-44. doi: 10.1111/j.1743-6109.2009.01408.x. Epub 2009 Jul 28.
Parkinson's disease (PD) presents unique personal and social challenges, particularly for those with onset before the age of 50 years.
The aim of this article is to evaluate sexual and non-sexual aspects of relationship satisfaction among persons with young-onset PD and their partners.
The main outcome measures were Index of Sexual Satisfaction (ISS) and Golombok-Rust Inventory of Marital State (GRIMS).
Persons with PD (PWP) and partners who attended the 2005 National Parkinson Foundation Young Onset Network Conference were asked to complete a survey. Each survey included demographics, a clinical history questionnaire, the Beck Depression Inventory (BDI), ISS, and GRIMS.
Sixty PWP (63% men, 85% in a relationship) responded to the survey. Median age was 50 years (range 29-62), with a median age at symptom onset of 43 years (range 17-55). ISS scores indicated clinically significant sexual dissatisfaction in 37%. Relationship dissatisfaction measured by the GRIMS was scored as "poor" or worse in 57%. Depressive symptomatology was severe in 19% and mild in 33%. Sexual dissatisfaction (ISS) correlated with relationship dissatisfaction (GRIMS) (correlation coefficient [CC] = 0.58, P < 0.001). Relationship dissatisfaction (GRIMS) correlated with depressive symptomatology (BDI) (CC = 0.38, P = 0.007). No correlations were found with any demographic or disease characteristics. Thirty-two couples (both the PWP and their partner) completed the surveys. Sexual and relationship dissatisfaction among PWP paralleled that of their partner (ISS: CC = 0.48, P = 0.005; GRIMS: CC = 0.61, P < 0.001). Depressive symptomatology of the PWP correlated with their partners' relationship dissatisfaction (CC = 0.46, P = 0.010).
In this study, sexual and relationship dissatisfaction were prevalent among young-onset PD patients. PD patients were similar to their partners in their level of sexual and relationship dissatisfaction. The degree of dissatisfaction did not correlate with demographics or self-reported disease characteristics. Self-reported depressive symptomatology among PD patients was adversely associated with both their and their partner's relationship satisfaction. Wiel
帕金森病（PD）给患者带来独特的个人和社会挑战，尤其是在 50 岁之前发病的患者。
本文旨在评估早发性帕金森病患者及其伴侣的性关系满意度的性和非性方面。
主要观察指标为性满意度指数（ISS）和戈勒姆-拉斯特婚姻状况量表（GRIMS）。
参加 2005 年国家帕金森基金会早发性网络会议的早发性 PD 患者（PWP）及其伴侣被要求完成一份调查。每份调查都包括人口统计学、临床病史问卷、贝克抑郁量表（BDI）、ISS 和 GRIMS。
60 名 PWP（63%为男性，85%有伴侣）对调查做出了回应。中位年龄为 50 岁（范围 29-62），中位发病年龄为 43 岁（范围 17-55）。ISS 评分显示 37%的患者存在明显的性不满足。GRIMS 测量的关系不满意评分在 57%为“差”或更差。19%的患者有严重的抑郁症状，33%的患者有轻度抑郁症状。性不满足（ISS）与关系不满足（GRIMS）呈正相关（相关系数[CC] = 0.58，P < 0.001）。关系不满足（GRIMS）与抑郁症状（BDI）呈正相关（CC = 0.38，P = 0.007）。与任何人口统计学或疾病特征均无相关性。32 对夫妇（PWP 及其伴侣）完成了调查。PWP 的性和关系不满足与他们的伴侣相似（ISS：CC = 0.48，P = 0.005；GRIMS：CC = 0.61，P < 0.001）。PWP 的抑郁症状与伴侣的关系不满意相关（CC = 0.46，P = 0.010）。
在这项研究中，早发性 PD 患者中普遍存在性和关系不满足。PD 患者与他们的伴侣在性和关系不满足方面相似。不满程度与人口统计学或自我报告的疾病特征无关。PD 患者的自我报告抑郁症状与他们和他们的伴侣的关系满意度均呈负相关。
