Schouteeten Stéphanie, Allen Olivia R, Haley Aireal D, Ong Grace L, Jones Gavin D, Vicic David A
Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR 72701.
J Organomet Chem. 2006 Nov 15;691(23):4975-4981. doi: 10.1016/j.jorganchem.2006.08.083.
Reaction of isopropyl[(2-pyridyl)alkyl]amines such as N-isopropyl-N-2-methylpyridine or N-isopropyl-N-2-ethylpyridine with aqueous solutions of NaAuCl(4) led to the formation of [LAuCl(2)][AuCl(4)] in low yields, where L = pyridyl amine bound to gold in a bidentate fashion. Reaction of 2-(3,5-diphenyl-1H-pyrrol-2-yl)pyridine with aqueous NaAuCl(4), however, proceeded with formal loss of HCl and direct formation of the gold(III) amido complex L'AuCl(2), where L' = deprotonated pyrrolyl ligand. Optimization of the reaction conditions to make the new amido complex identified MeCN:H(2)O (1:2) as the best choice of solvent, affording product in 92 % yield. This dichloro amido complex is a convenient precursor to L'AuMe(2), which was found to be air-stable and thermally robust.
异丙基[(2-吡啶基)烷基]胺（如N-异丙基-N-2-甲基吡啶或N-异丙基-N-2-乙基吡啶）与NaAuCl₄水溶液反应，以低产率生成[LAuCl₂][AuCl₄]，其中L = 以双齿方式与金结合的吡啶基胺。然而，2-(3,5-二苯基-1H-吡咯-2-基)吡啶与NaAuCl₄水溶液反应时，伴随着HCl的形式损失并直接形成金(III)酰胺配合物L'AuCl₂，其中L' = 去质子化的吡咯基配体。对反应条件进行优化以制备新的酰胺配合物，结果表明MeCN:H₂O (1:2)是最佳的溶剂选择，产物收率为92%。这种二氯酰胺配合物是制备L'AuMe₂的便利前体，发现L'AuMe₂对空气稳定且热稳定性好。
