Bruzzese V
Ospedale S. Giacomo in Augusta, Roma.
Clin Ter. 1990 Dec 31;135(6):483-6.
The case is described of a patient suffering from pulmonary microcytoma the initial symptoms of which were attributable to the ectopic production of the different hormonal substances by the neoplastic cells. In fact, the patient presented the classical picture of inappropriate ADH secretion associated with hypoglycemic crises caused y hyperinsulinemia. The extreme rarity of the twofold paraneoplastic syndrome in the course of malignant disease and the peculiarity of microcytoma associated with inappropriate ADH secretion and hypoglycemia is stressed.
本文描述了一名患有肺微细胞瘤的患者,其最初症状归因于肿瘤细胞异位产生的不同激素物质。事实上,该患者呈现出与高胰岛素血症引起的低血糖危象相关的抗利尿激素分泌不当的典型症状。文中强调了在恶性疾病过程中这种双重副肿瘤综合征的极端罕见性,以及微细胞瘤与抗利尿激素分泌不当和低血糖相关的特殊性。