Milleron B, Roger V, Roux P, Lebreton C, Koeger A, Dupont B, Akoun G
Service de Pneumologie, Hôpital Tenon, Paris.
Rev Pneumol Clin. 1990;46(4):175-7.
Pulmonary aspergillosis invading the thoracic wall is rare and of sombre prognosis. We report the case of a 49-year old man who developed a pulmonary aspergilloma some time after lung resection and radiotherapy for bronchial adenocarcinoma. Surgical excision of the aspergilloma was followed by sternal, then costal aspergillosis. Conventional surgery and antifungal therapy failed, and the lesion stubbornly followed a chronic course until itraconazole therapy was instituted, resulting in a complete cure which still persists nearly 4 years after withdrawal of any chemotherapy.
侵袭胸壁的肺曲霉菌病较为罕见，预后不良。我们报告一例49岁男性病例，该患者在因支气管腺癌接受肺切除和放疗后一段时间患上了肺曲菌球。曲菌球手术切除后，继而出现胸骨、然后是肋骨曲霉菌病。传统手术和抗真菌治疗均告失败，病变顽固地呈慢性病程，直至开始使用伊曲康唑治疗，最终实现完全治愈，在停止任何化疗近4年后仍未复发。
