Bui S, Babre F, Hauchecorne S, Christoflour N, Ceccato F, Boisserie-Lacroix V, Clouzeau H, Fayon M
CHU de Bordeaux, Hôpital Pellegrin-Enfants, CRCM Pédiatrique, France.
J Cyst Fibros. 2009 Sep;8(5):326-31. doi: 10.1016/j.jcf.2009.07.002. Epub 2009 Aug 5.
We aimed to evaluate the use of central catheters introduced by a peripheral vein (PICC) in children with CF.
A descriptive study in patients in whom a PICC (Beckton Dickinson) was inserted.
24 children aged (median (range) 10.2 years (0.3-17.3) undergoing 44 procedures were included. PICC was successfully inserted in 93.2% (41/44) of cases. Total procedure duration was (median (range)) 32.5 (10-105) minutes. The operators encountered few difficulties, median (range) 2 (1-10) (1 (absence) to 10 (maximal)); median (range) 1 (1 to 5) attempt per child). No major side effects or infections were observed. PICC obstruction in 5 (12%) cases was successfully unblocked in 4 cases (urokinase). The catheter was functional throughout the antibiotic course in 40/41 cases. A final Doppler scan (30 cases) showed total permeability of the central veins in all cases. Satisfaction index of the operators and the patients were high: median (range) 9.5 (1-10) and 8.0 (6-10) (scale: 1 (worse) to 10 (best)), respectively.
PICCs are simple to use, and may be safely inserted in the ward. Such catheters are well tolerated, may increase the well-being of children with CF and prove an effective means by which to deliver IV therapy in this population.
我们旨在评估经外周静脉置入中心静脉导管（PICC）在囊性纤维化（CF）患儿中的应用情况。
对置入PICC（贝克顿·迪金森公司产品）的患者进行描述性研究。
纳入了24名年龄（中位数（范围））为10.2岁（0.3 - 17.3岁）的儿童，共进行了44次操作。PICC在93.2%（41/44）的病例中成功置入。总操作时间为（中位数（范围））32.5（10 - 105）分钟。操作人员遇到的困难较少，中位数（范围）为2（1 - 10）（1表示无困难至10表示最大困难）；每个儿童的操作尝试次数中位数（范围）为1（1 - 5）次。未观察到重大副作用或感染情况。5例（12%）出现PICC堵塞，其中4例（使用尿激酶）成功疏通。在41例中的40例中，导管在整个抗生素疗程中功能良好。最终的多普勒扫描（30例）显示所有病例的中心静脉完全通畅。操作人员和患者的满意度指数较高：分别为中位数（范围）9.5（1 - 10）和8.0（6 - 10）（评分标准：1表示最差至10表示最佳）。
PICC使用简便，可在病房安全置入。此类导管耐受性良好，可能会提高CF患儿的舒适度，并证明是在该人群中进行静脉治疗的有效手段。
