Pelosi Giuseppe, Sonzogni Angelica, Viale Giuseppe
Division of Pathology and Laboratory Medicine, European Institute of Oncology and University of Milan School of Medicine, Milan, Italy.
Int J Surg Pathol. 2011 Aug;19(4):518-20. doi: 10.1177/1066896909341800. Epub 2009 Aug 5.
Intravascular papillary endothelial hyperplasia (IPEH) is a benign, florid proliferation of endothelial cells forming hyaline papillae covered by monolayered cells, which has rarely been described in the renal vein, most often being equated to tumors because of the difficulties in correctly interpreting imaging findings and accordingly treated by nephrectomy. If the kidney is end-staged for preexisting medical diseases, the risk of overtreatment is obviously negligible, but overdiagnosing IPEH as an intravascular tumor, either benign or malignant, may be perilous for the patient because of the possible consequences on the clinical management.
血管内乳头状内皮增生(IPEH)是一种良性的、内皮细胞的旺盛增殖,形成由单层细胞覆盖的透明乳头,肾静脉中很少有相关描述,由于难以正确解读影像学表现,它常被等同于肿瘤,并因此接受肾切除术治疗。如果肾脏因既往存在的内科疾病而处于终末期,过度治疗的风险显然可以忽略不计,但将IPEH过度诊断为良性或恶性血管内肿瘤,可能会因对临床管理产生的潜在影响而给患者带来危险。