基于顺磁性钆的金糖纳米颗粒作为磁共振成像探针：通过糖类调节弛豫率。
Paramagnetic Gd-based gold glyconanoparticles as probes for MRI: tuning relaxivities with sugars.
作者信息
Marradi Marco, Alcántara David, de la Fuente Jesús Martínez, García-Martín María Luisa, Cerdán Sebastián, Penadés Soledad
机构信息
Laboratory of GlycoNanotechnology, CIC biomaGUNE/CIBER-BBN and IIQ-CSIC, Parque Tecnológico de San Sebastián, San Sebastián, Spain.
出版信息
Chem Commun (Camb). 2009 Jul 14(26):3922-4. doi: 10.1039/b900957d. Epub 2009 May 20.
DOI:10.1039/b900957d
PMID:19662253
Abstract
Combining sugar conjugates and DO3A-Gd complexes, paramagnetic gold glyconanoparticles (GNPs) with different relaxivity values were obtained and tested in vivo as MRI probes.
摘要
通过将糖缀合物与DO3A-钆配合物相结合，获得了具有不同弛豫率值的顺磁性金糖纳米颗粒（GNP），并作为磁共振成像（MRI）探针进行了体内测试。
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