Tafeit Erwin, Greilberger Joachim, Cvirn Gerhard, Lipp Rainer Walther, Schnedl Wolfgang Johann, Jürimäe Toivo, Jürimäe Jaak, Wallner-Liebmann Sandra Johanna
Institute of Physiological Chemistry, Center for Physiological Medicine, Medical University Graz, Graz, Austria.
Coll Antropol. 2009 Jun;33(2):391-6.
DXA is an accepted reference method to estimate body composition. However several difficulties in the applicability exist. The equipment is rather expensive, not portable, impractical for measurement of big study populations and it provides a minimal amount of ionizing radiation exposure. The optical device Lipometer (EU Pat.No. 0516251) provides non-invasive, quick, precise and safe measurements of subcutaneous adipose tissue (SAT) layer thicknesses at any site of the human body. Compared to DXA there are some advantages in the Lipometer approach, because this device is portable, quick, not expensive and no radiation is involved. To use these advantages in the field of total body fat% (TBF%) assessment, an acceptable estimation of DXA TBF% by Lipometer SAT thicknesses is necessary, which was the aim of this study. Height, weight, waist and hip circumferences, DXA TBF% and Lipometer SAT thicknesses at fifteen defined body sites were measured in 28 healthy men (age: 33.9 +/- 16.6 years) and 52 healthy women (age: 40.1 +/- 10.7 years). To estimate Lipometer TBF% stepwise multiple regression analysis was applied, using DXA TBF% as dependent variable. Using the fifteen Lipometer SAT thicknesses together with age, height, weight and BMI as independent variables provided the best estimations of Lipometer TBF% for both genders with strong correlations to DXA TBF% (R = 0.985 for males and R = 0.953 for females). The limits of agreement were -2.48% to +2.48% for males and -4.28% to + 4.28% for females. For both genders we received a bias of 0.00%. The results of this paper extend the abilities of the Lipometer by a precise estimation of TBF% using DXA as golden standard.
双能X线吸收法(DXA)是一种公认的用于估计身体成分的参考方法。然而,其在适用性方面存在一些困难。该设备相当昂贵,不便于携带,对于大规模研究人群的测量不实用,并且会产生少量电离辐射暴露。光学设备Lipometer(欧盟专利号0516251)可对人体任何部位的皮下脂肪组织(SAT)层厚度进行非侵入性、快速、精确且安全的测量。与DXA相比,Lipometer方法具有一些优势,因为该设备便于携带、速度快、价格不贵且不涉及辐射。为了在全身脂肪百分比(TBF%)评估领域利用这些优势,有必要通过Lipometer测量的SAT厚度对DXA的TBF%进行可接受的估计,这就是本研究的目的。对28名健康男性(年龄:33.9±16.6岁)和52名健康女性(年龄:40.1±10.7岁)测量了身高、体重、腰围和臀围、DXA的TBF%以及在15个定义身体部位的Lipometer测量的SAT厚度。为了估计Lipometer的TBF%,采用逐步多元回归分析,将DXA的TBF%作为因变量。将15个Lipometer测量的SAT厚度与年龄、身高、体重和体重指数作为自变量一起使用,对两种性别而言,能对Lipometer的TBF%提供最佳估计,且与DXA的TBF%具有强相关性(男性R = 0.985,女性R = 0.953)。男性的一致性界限为-2.48%至+2.48%,女性为-4.28%至+4.28%。两种性别均得到偏差为0.00%。本文的结果通过以DXA作为金标准精确估计TBF%,扩展了Lipometer的功能。