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Characterization of attenuated mutants of MHV3: importance of the E2 protein in organ tropism and infection of isolated liver cells.

作者信息

Martin J P, Chen W, Obert G, Koehren F

机构信息

Laboratoire de Virologie de la Faculté de Médecine et Unité, INSERM 74, Strasbourg.

出版信息

Adv Exp Med Biol. 1990;276:403-10. doi: 10.1007/978-1-4684-5823-7_55.

DOI:10.1007/978-1-4684-5823-7_55
PMID:1966430
Abstract
摘要

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The spike protein of murine coronavirus mouse hepatitis virus strain A59 is not cleaved in primary glial cells and primary hepatocytes.鼠冠状病毒A59株的刺突蛋白在原代神经胶质细胞和原代肝细胞中不会被切割。
J Virol. 1998 Feb;72(2):1606-9. doi: 10.1128/JVI.72.2.1606-1609.1998.
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The virulence of mouse hepatitis virus 3, as evidenced by permissivity of cultured hepatic cells toward escape mutants.
小鼠肝炎病毒3的毒力，由培养的肝细胞对逃逸突变体的易感性所证明。
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