Feeney J N, Fox J J, Akhurst T
Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Clin Radiol. 2009 Sep;64(9):897-902. doi: 10.1016/j.crad.2009.05.004. Epub 2009 Jul 5.
To report a case series in which the radiological features of the subcutaneous use of calcium hydroxylapatite (CaHa) dermal fillers are described for the first time.
Five patients with facial hyperattenuating hypermetabolic subcutaneous lesions were identified on 2- [(18)F]-fluoro-2-deoxy-D-glucose (FDG) positron-emission tomography/computed tomography (PET/CT), who gave a history of facial injections to augment physical appearance. Correlation with additional imaging studies was performed.
All cases had subcutaneous high attenuation material on CT (range 280-700HU), which was FDG avid on PET, with a standardized uptake value (SUV) range of 2.9-13.4. Magnetic resonance imaging (MRI) demonstrated a heterogeneous intermediate signal intensity subcutaneous lesion with enhancement post-gadolinium in one case.
CaHa dermal filler is hyperattenuating on CT, hypermetabolic on FDG-PET imaging, of intermediate signal intensity on MRI, and is a potential cause of a false-positive imaging study.
报告一系列病例，首次描述皮下使用羟基磷灰石钙（CaHa）真皮填充剂的放射学特征。
在2-[(18)F]-氟-2-脱氧-D-葡萄糖（FDG）正电子发射断层扫描/计算机断层扫描（PET/CT）上识别出5例面部皮下病变呈高衰减、高代谢的患者，这些患者有面部注射以改善外貌的病史。并与其他影像学检查进行了相关性分析。
所有病例在CT上均有皮下高衰减物质（范围为280-700HU），在PET上呈FDG摄取，标准化摄取值（SUV）范围为2.9-13.4。磁共振成像（MRI）显示1例皮下病变信号强度不均一，呈中等强度，钆剂增强后强化。
CaHa真皮填充剂在CT上呈高衰减，在FDG-PET成像上呈高代谢，在MRI上呈中等信号强度，是影像学检查假阳性的潜在原因。
