Ng Valerie L
Department of Laboratory Medicine, School of Medicine, University of California San Francisco, San Francisco, CA, USA.
Clin Lab Med. 2009 Jun;29(2):253-63. doi: 10.1016/j.cll.2009.05.002.
Prothrombin times and activated partial thromboplastin times have long been used as tests of overall ("global") clotting function. Laboratory coagulation testing issues should be at the forefront of the reader's consciousness whenever critically evaluating and extrapolating published study conclusions reliant on the results of these tests. Thus, this article reviews laboratory issues and known variables influencing prothrombin time and partial thromboplastin time results and international normalized ratio determinations.
凝血酶原时间和活化部分凝血活酶时间长期以来一直被用作整体(“全面”)凝血功能的检测指标。每当批判性地评估和推断依赖于这些检测结果的已发表研究结论时,实验室凝血检测问题都应处于读者意识的前沿。因此,本文回顾了影响凝血酶原时间、部分凝血活酶时间结果及国际标准化比值测定的实验室问题和已知变量。