Alzheimer's Disease Clinical and Research Program, Boston University, Boston, Massachusetts, USA.
J Pain. 2010 Jan;11(1):62-70. doi: 10.1016/j.jpain.2009.06.005. Epub 2009 Aug 8.
Prevalence of tender points (TP), and widespread pain and fibromyalgia, as well as the relationship between TP and widespread pain and mobility, was examined in 585 community-dwelling older adults (mean age 78.2 years, 63.4% female). Pain was based on location (none, single site, multisite, widespread). Mobility was measured by the Short Physical Performance Battery (SPPB), gait speed, and self-reported (S-R) mobility difficulty. Tender-point count and health characteristics (ie, BMI, chronic conditions, analgesic use, number of medications, depression, and blocks walked per week) were assessed. Several participants had 3 or more TP (22.1%) although prevalence of criteria-based fibromyalgia was low (.3%). Mobility was more limited in persons with higher tender-point counts. After adjustment for pain and other risk factors, higher tender-point count was associated with poorer SPPB performance (score < 10, aOR = 1.09 per TP, 95%CI, 1.01-1.17), and slow gait speed (< .784m/sec, aOR = 1.14 per TP, 95%CI, 1.05-1.24), but not with S-R mobility difficulty. S-R mobility difficulty was associated with more disseminated pain (multisite pain, aOR = 2.01, 95%CI, 1.21-3.34; widespread pain, aOR = 2.47, 95%CI, 1.09-5.62). These findings portray a significant mobility burden related to tender-point count and multisite and widespread pain in the older population. Future studies using longitudinal methods are warranted.
Higher tender-point count, multisite pain, and widespread pain are common in community-dwelling older adults and associated with mobility problems. Both the manual tender-point exam and the McGill Pain Map may provide important yet different information about risks for mobility disability in older individuals.
本研究调查了 585 名居住在社区的老年人(平均年龄 78.2 岁,63.4%为女性)中压痛点(TP)、广泛疼痛和纤维肌痛的流行情况,以及 TP 与广泛疼痛和活动能力之间的关系。疼痛基于部位(无、单部位、多部位、广泛)。活动能力通过简短体能测试(SPPB)、步态速度和自我报告(S-R)的活动能力困难程度来衡量。压痛点数和健康特征(即 BMI、慢性疾病、镇痛药使用、用药数量、抑郁和每周步行的街区数)进行了评估。尽管基于标准的纤维肌痛的患病率较低(0.3%),但仍有多名参与者存在 3 个或更多的 TP(22.1%)。TP 计数较高的人活动能力受限更为明显。在调整疼痛和其他风险因素后,较高的压痛点数与较差的 SPPB 表现相关(评分<10,TP 每增加一个的优势比为 1.09,95%可信区间为 1.01-1.17),以及较慢的步态速度(<0.784m/sec,TP 每增加一个的优势比为 1.14,95%可信区间为 1.05-1.24),但与 S-R 活动能力困难无关。S-R 活动能力困难与更广泛的疼痛(多部位疼痛,优势比为 2.01,95%可信区间为 1.21-3.34;广泛疼痛,优势比为 2.47,95%可信区间为 1.09-5.62)相关。这些发现描绘了与老年人压痛点数、多部位疼痛和广泛疼痛相关的显著活动能力负担。未来使用纵向方法的研究是必要的。
在居住在社区的老年人中,较高的压痛点数、多部位疼痛和广泛疼痛很常见,并与活动能力问题相关。手动压痛检查和麦吉尔疼痛图都可能提供关于老年人活动能力残疾风险的重要但不同的信息。