Liu Zhengyu, Habener Joel F
Laboratory of Molecular Endocrinology, Massachusetts General Hospital, Boston, MA 02114, USA.
Cell. 2009 Aug 7;138(3):424-6. doi: 10.1016/j.cell.2009.07.022.
Understanding the origins of insulin-producing beta cells of the pancreas could lead to new treatments for diabetes. Collombat et al. (2009) now show that in response to injury, a population of pancreatic progenitor cells can give rise to glucagon-expressing alpha cells that then transdifferentiate into beta cells.
了解胰腺中产生胰岛素的β细胞的起源可能会带来糖尿病的新疗法。科洛姆巴特等人（2009年）现在表明，在受到损伤时，一群胰腺祖细胞可以产生表达胰高血糖素的α细胞，然后这些α细胞会转分化为β细胞。
