亚洲男性是否应纳入腹主动脉瘤筛查项目？
Should Asian men be included in abdominal aortic aneurysm screening programmes?
作者信息
Salem M K, Rayt H S, Hussey G, Rafelt S, Nelson C P, Sayers R D, Naylor A R, Nasim A
机构信息
Department of Vascular & Endovascular Surgery, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom.
出版信息
Eur J Vasc Endovasc Surg. 2009 Dec;38(6):748-9. doi: 10.1016/j.ejvs.2009.07.012. Epub 2009 Aug 8.
INTRODUCTION
A national AAA screening programme for men aged 65 is shortly to be implemented in England. Trials that have provided evidence for this screening programme have not included information on ethnicity. Hence their findings may not be applicable to ethnically diverse populations.
REPORT
This study retrospectively looked at the prevalence of AAA in men aged 65, from different ethnic backgrounds in our city's current screening programme.19014 men (Caucasians n=18,431, Asian n=446, others n=137) were screened. Prevalence was 4.69% (4.39-5% 95% CI), and 0.45% (0.054-1.161% 95% CI) in Caucasians and Asians respectively (Fisher's exact test: P<0.0001).
DISCUSSION
Prevalence of AAAs in men aged 65 of Asian origin appears to be low and so increases uncertainty about cost-effectiveness of screening Asian men.
引言
一项针对65岁男性的全国性腹主动脉瘤筛查计划即将在英格兰实施。为该筛查计划提供证据的试验未包含种族信息。因此，其研究结果可能不适用于种族多样化的人群。
报告
本研究回顾性地观察了我市当前筛查计划中不同种族背景的65岁男性腹主动脉瘤的患病率。共筛查了19014名男性（白种人n = 18431，亚洲人n = 446，其他种族n = 137）。白种人和亚洲人的患病率分别为4.69%（4.39 - 5% 95%置信区间）和0.45%（0.054 - 1.161% 95%置信区间）（费舍尔精确检验：P < 0.0001）。
讨论
亚洲裔65岁男性腹主动脉瘤的患病率似乎较低，这增加了对筛查亚洲男性成本效益的不确定性。
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