Mejía-Rivas M, Remes-Troche J M, Montaño-Loza A, Herrera M, Valdovinos-Díaz M A
Gastroenterology and Surgery Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Rev Gastroenterol Mex. 2009;74(1):71-3.
The role of gastrointestinal function in obesity is unknown. Recent studies have shown that satiety in obese patients is influenced by an abnormal gastric capacity.
An easy and non-invasive tool, the water load test (WLT) was used to evaluate gastric capacity and how it relates to body mass index (BMI) in obese patients.
The WLT was performed in 32 patients with high BMI and 12 healthy volunteers. Water was ingested at a 15 mL/min rate. The maximal tolerable volume (MTV) was defined as the total ingested volume when patients stopped the test.
A BMI > 30 was significantly associated with higher water consumption (2339 ± 306 mL) compared to controls (1830 ± 240 mL, p = 0.001). The MTV had a positive correlation with BMI (r = 0.68, p = 0.001).
Obese subjects have an increased gastric capacity, as measured with the WLT. This greater drinking capacity has a positive correlation with the subjects' BMI.
胃肠功能在肥胖症中的作用尚不清楚。近期研究表明，肥胖患者的饱腹感受胃容量异常影响。
使用一种简便且无创的工具——水负荷试验（WLT）来评估肥胖患者的胃容量及其与体重指数（BMI）的关系。
对32名高BMI患者和12名健康志愿者进行水负荷试验。以15毫升/分钟的速率摄入水。最大耐受量（MTV）定义为患者停止试验时的总摄入量。
与对照组（1830±240毫升，p = 0.001）相比，BMI>30与更高的饮水量（2339±306毫升）显著相关。MTV与BMI呈正相关（r = 0.68，p = 0.001）。
用水负荷试验测量发现，肥胖受试者的胃容量增加。这种更大的饮水能力与受试者的BMI呈正相关。
