Delbem Alberto Carlos Botazzo, Brighenti Fernanda Lourenção, Oliveira Felipe Alberto Lino, Pessan Juliano Pelin, Buzalaf Marília Afonso Rabelo, Sassaki Kikue Takebayashi
Araçatuba Dental School, São Paulo State University, Araçatuba, SP, Brazil.
J Appl Oral Sci. 2009 Jul-Aug;17(4):280-3. doi: 10.1590/s1678-77572009000400003.
The time of contact between the product and enamel surface is important in ensuring the efficacy of fluoride varnishes. Thus, some alternatives could avoid fluoride loss to saliva and improve the anticariogenic action of the product. This study evaluated the effect of an experimental coat on the anticariogenic action of fluoride varnishes.
Enamel bovine blocks were selected by evaluating surface microhardness and randomized into five groups (n=24): placebo, Duraphat, Duraphat with coat, Duofluorid and Duofluorid with coat. Twelve blocks from each group were used to analyze calcium fluoride (CaF2) formed on enamel after treatment. The other 12 blocks were subjected to pH cycling for 7 days. The varnishes were kept on enamel for 6 h. Next, the percentage change of surface microhardness (%SMHC) and mineral loss (DeltaZ) were calculated. CaF2 retained and fluoride present in the pH-cycled solutions were also measured.
The use of the coat did not decrease %SMHC and DeltaZ, but all fluoride varnishes had better results when compared to the placebo (ANOVA and Kruskal-Wallis, respectively). The values from CaF2 formed were higher compared to the values of CaF2 retained (non-paired t test, p<0.05). There was a trend to decrease the amount of F in the solutions at the end of pH cycling (Kruskal-Wallis, p<0.05).
Although the experimental coat increased the formation of CaF2 on the enamel surface, it did not significantly improve the anticariogenic action of fluoride varnishes.
产品与牙釉质表面的接触时间对于确保氟化物漆的疗效很重要。因此，一些替代方法可以避免氟化物流失到唾液中，并提高产品的防龋作用。本研究评估了一种实验性涂层对氟化物漆防龋作用的影响。
通过评估表面显微硬度选择牛牙釉质块，并随机分为五组（n = 24）：安慰剂组、Duraphat组、涂有涂层的Duraphat组、Duofluorid组和涂有涂层的Duofluorid组。每组的12个牙釉质块用于分析处理后牙釉质上形成的氟化钙（CaF2）。另外12个牙釉质块进行7天的pH循环。将氟化物漆保留在牙釉质上6小时。接下来，计算表面显微硬度百分比变化（%SMHC）和矿物质损失（ΔZ）。还测量了pH循环溶液中保留的CaF2和存在的氟化物。
使用涂层并未降低%SMHC和ΔZ，但与安慰剂相比，所有氟化物漆的效果都更好（分别为方差分析和克鲁斯卡尔-沃利斯检验）。形成的CaF2值高于保留的CaF2值（非配对t检验，p < 0.05）。在pH循环结束时，溶液中的氟含量有降低的趋势（克鲁斯卡尔-沃利斯检验，p < 0.05）。
尽管实验性涂层增加了牙釉质表面CaF2的形成，但并未显著提高氟化物漆的防龋作用。
