对巴基斯坦费萨拉巴德慢性丙肝患者的血清、唾液和尿液样本中丙肝病毒（HCV）的同时存在情况进行调查。
Investigating the concurrent presence of HCV in serum, oral fluid and urine samples from chronic HCV patients in Faisalabad, Pakistan.
作者信息
Shafique Muhammad, Ahmad Nasir, Awan Fazli R, Mustafa Tanveer, Ullah Mujib, Qureshi Javed A
机构信息
Health Biotechnology Division, National Institute for Biotechnology and Genetic Engineering, P.O. Box 577, Jhang Road, Faisalabad, Pakistan.
出版信息
Arch Virol. 2009;154(9):1523-7. doi: 10.1007/s00705-009-0477-7. Epub 2009 Aug 8.
Hepatitis C virus (HCV) is normally present in the blood of infected patients; however, it can also be present in some other body fluids. Therefore, in this study, a concurrent presence of HCV-RNA was investigated in oral fluid and urine of 80 Pakistani chronic HCV patients. HCV-RNA was detected in 31 (38.8%) oral fluid and 10 (12.5%) urine samples using RT-PCR in all 80 of the patients whose sera tested positive for HCV-RNA. From this study, it is concluded that, in addition to the blood, HCV RNA can also be found in oral secretions as well as urine of chronic HCV patients.
丙型肝炎病毒（HCV）通常存在于受感染患者的血液中；然而，它也可能存在于其他一些体液中。因此，在本研究中，对80名巴基斯坦慢性丙型肝炎患者的口腔液和尿液中HCV-RNA的同时存在情况进行了调查。在所有80名血清HCV-RNA检测呈阳性的患者中，使用逆转录聚合酶链反应（RT-PCR）在31份（38.8%）口腔液和10份（12.5%）尿液样本中检测到了HCV-RNA。从这项研究可以得出结论，除血液外，慢性丙型肝炎患者的口腔分泌物和尿液中也能发现HCV RNA。
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