Institute of General Zoology and Endocrinology, University of Ulm, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Cell Mol Life Sci. 2009 Dec;66(24):3837-50. doi: 10.1007/s00018-009-0112-5.
Several reviews devoted to various aspects of ecdysone research have been published during the last few years. Therefore, this article concentrates mainly on the considerable progress in ecdysone research observed recently, and will cover the results obtained during the last 2 years. The main emphasis is put on the molecular mode of ecdysteroid receptor-mediated hormone action. Two examples of interaction with other hormonal signalling pathways are described, namely crosstalk with juvenile hormone and insulin. Some selected, recently investigated examples of the multitude of hormonal responses are described. Finally, ecological aspects and some practical applications are discussed.
近年来,有几篇专门讨论蜕皮激素研究各个方面的综述已经发表。因此,本文主要集中于最近观察到的蜕皮激素研究的相当大的进展,并将涵盖过去 2 年取得的成果。重点主要放在蜕皮甾酮受体介导的激素作用的分子模式上。描述了与其他激素信号通路相互作用的两个例子,即与保幼激素和胰岛素的交叉作用。还描述了最近研究的众多激素反应的一些选定例子。最后,讨论了生态方面和一些实际应用。