Hafezi F, Moesen I, Carels G, Mooy C, Paridaens D
IROC, Institut für Refraktive und Ophthalmo-Chirurgie, Zürich, Schweiz.
Ophthalmologe. 2010 Jan;107(1):60-3. doi: 10.1007/s00347-009-2010-5.
We report a case of bilateral lacrimal gland involvement as the first sign of Waldenstrom's macroglobulinaemia in a patient with sarcoidosis. Histological analysis of an incisional biopsy revealed a lymphoplasmocytic lymphoma consistent with Waldenstrom's macroglobulinaemia. No noncaseating granulomas were encountered. Systemic treatment was initiated and resulted in complete resolution of the lesions. In a patient with a systemic disease, such as sarcoidosis, and lacrimal gland involvement, a biopsy of the lacrimal gland mass should be taken to make a correct diagnosis and start appropriate treatment.
我们报告一例结节病患者双侧泪腺受累作为华氏巨球蛋白血症首发体征的病例。切开活检的组织学分析显示为符合华氏巨球蛋白血症的淋巴浆细胞淋巴瘤。未发现非干酪样肉芽肿。开始进行全身治疗,病变完全消退。对于患有结节病等全身性疾病且泪腺受累的患者,应进行泪腺肿物活检以做出正确诊断并开始适当治疗。