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[围手术期疼痛治疗的概念。一次批判性评估]

[Concepts for perioperative pain therapy. A critical stocktaking].

作者信息

Reichl S, Pogatzki-Zahn E

机构信息

Klinik und Poliklinik für Anästhesiologie und operative Intensivmedizin, Universitätsklinikum, Albert-Schweitzer-Str. 33, 48129, Münster, Deutschland.

出版信息

Anaesthesist. 2009 Sep;58(9):914-6, 918-20, 922-6 passim. doi: 10.1007/s00101-009-1589-x.

Abstract

Despite numerous publications, new guidelines for the treatment of acute pain and efforts from a number of initiatives, there is still a tremendous need for improvement in postoperative pain therapy. One of the reasons for the shortcomings in the care of patients with postoperative pain is the lack of applicability of guidelines in daily clinical practice. Therefore, simple but effective and easy to implement concepts need to be developed. In the following review, different concepts that have been developed over recent years are presented and evaluated for their effectiveness. One of these is the notion of balanced analgesia, currently probably one of the most widely used perioperative therapy concepts. The idea of this concept is to reduce the doses of analgesics, e.g. opioids, through combinations of different classes of analgesics, thereby reducing their side effects. However, recent studies and essential meta-analyses indicate pitfalls using this concept. The pros and cons will be discussed and ideas on how to deal with balanced analgesia in daily practice will be given. Another pain concept of "procedure-specific postoperative pain therapy", is an appealing idea of an international initiative from surgeons and anaesthesiologists and an essential part of the German S3 guidelines for acute pain released last year. Critical evaluation of the available recommendations for procedure-specific analgesia together with the presentation of relatively simple but evidence-based algorithms for specific procedures may help to implement this concept in clinical routine.

摘要

尽管有大量相关出版物、急性疼痛治疗的新指南以及多项倡议所做的努力,但术后疼痛治疗仍有极大的改进需求。术后疼痛患者护理存在不足的原因之一是指南在日常临床实践中缺乏适用性。因此,需要制定简单但有效且易于实施的理念。在以下综述中,介绍了近年来形成的不同理念,并对其有效性进行评估。其中之一是平衡镇痛的概念,目前它可能是围手术期治疗中使用最广泛的理念之一。该理念的核心是通过联合使用不同类别的镇痛药来减少镇痛药(如阿片类药物)的剂量,从而降低其副作用。然而,近期的研究和重要的荟萃分析表明该理念存在缺陷。本文将讨论其利弊,并给出在日常实践中应对平衡镇痛的思路。另一个疼痛理念即“针对特定手术的术后疼痛治疗”,是外科医生和麻醉医生发起的一项国际倡议中颇具吸引力的想法,也是去年发布的德国急性疼痛S3指南的重要组成部分。对针对特定手术的镇痛现有建议进行批判性评估,并展示针对特定手术相对简单但基于证据的算法,可能有助于在临床常规中实施这一理念。

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