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颈动脉支架置入术:11 年单中心经验。

Carotid artery stenting: single-center experience over 11 years.

机构信息

Department of Cardiovascular and Interventional Radiology, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.

出版信息

Cardiovasc Intervent Radiol. 2010 Apr;33(2):251-9. doi: 10.1007/s00270-009-9673-9. Epub 2009 Aug 11.

Abstract

This article reports the results of carotid artery stenting during an 11-year period. Data from 168 carotid artery stenting procedures (symptomatic, n = 55; asymptomatic, n = 101; symptoms not accessible, n = 12) were retrospectively collected. Primary technical success rate, neurological events in-hospital, access-site complications, and contrast-induced nephropathy (n = 118) were evaluated. To evaluate the influence of experience in carotid artery stenting on intraprocedural neurologic complications, patients were divided into two groups. Group 1 included the first 80 treated patients, and group 2 the remainder of the patients (n = 88). In-stent restenoses at last-follow-up examinations (n = 89) were assessed. The overall primary technical success rate was 95.8%. The in-hospital stroke-death rate was 3.0% (n = 5; symptomatic, 5.4%; asymptomatic, 2.0%; p = 0.346). Neurologic complications were markedly higher in group 1 (4.2%; three major strokes; symptomatic, 2.8%, asymptomatic, 1.4%) compared to group 2 (2.4%; one major and one minor stroke-symptomatic, 1.2%, asymptomatic 1.2%), but this was not statistically significant. Further complications were access-site complications in 12 (7.1%), with surgical revision required in 1 (0.6%) and mild contrast-induced nephropathy in 1 (0.85%). Twenty-one (23.6%) patients had >50% in-stent restenosis during a mean follow-up of 28.2 months. In conclusion, advanced experience in carotid artery stenting leads to an acceptable periprocedural stroke-death rate. In-stent restenosis could be a critical factor during the follow-up course.

摘要

这篇文章报告了 11 年间颈动脉支架置入术的结果。回顾性收集了 168 例颈动脉支架置入术(症状性,n = 55;无症状性,n = 101;症状不可评估,n = 12)的数据。评估了主要技术成功率、住院期间神经事件、入路部位并发症和对比剂肾病(n = 118)。为了评估颈动脉支架置入术经验对术中神经并发症的影响,将患者分为两组。第 1 组包括前 80 例患者,第 2 组包括其余患者(n = 88)。评估最后一次随访时的支架内再狭窄(n = 89)。总体主要技术成功率为 95.8%。住院期间的卒中死亡率为 3.0%(n = 5;症状性,5.4%;无症状性,2.0%;p = 0.346)。第 1 组(4.2%;3 例大卒中;症状性,2.8%,无症状性,1.4%)的神经并发症明显高于第 2 组(2.4%;1 例大卒中和 1 例小卒中-症状性,1.2%,无症状性,1.2%),但无统计学意义。进一步的并发症是 12 例(7.1%)入路部位并发症,其中 1 例(0.6%)需要手术修正,1 例(0.85%)发生轻度对比剂肾病。21 例(23.6%)患者在平均 28.2 个月的随访中存在>50%的支架内再狭窄。总之,颈动脉支架置入术的先进经验可导致可接受的围手术期卒中死亡率。支架内再狭窄可能是随访过程中的一个关键因素。

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