氰化物对花生脂氧合酶的影响。

Effects of cyanide on peanut lipoxygenase.

作者信息

St Angelo A J, Kuck J C

出版信息

Lipids. 1977 Aug;12(8):682-3. doi: 10.1007/BF02533765.

PMID:19672

Abstract

Acidic and alkaline lipoxygenase isozymes were separated and assayed for activity while incubated in the presence of various concentrations of cyanide. Inhibition due to cyanide per se was not found. Instead, cyanide caused an increase in pH, which decreased the activity of the acidic isozyme to a rate corresponding to the same pH on the activity curve for the cyanide-free reaction.

摘要

在存在不同浓度氰化物的情况下，对酸性和碱性脂氧合酶同工酶进行了分离并测定其活性。未发现氰化物本身导致抑制作用。相反，氰化物导致pH值升高，这使得酸性同工酶的活性降低至与无氰化物反应活性曲线上相同pH值对应的速率。