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评估骨科与创伤学中深静脉血栓形成预防方案的有效性。

Evaluating the effectiveness of a deep-vein thrombosis prophylaxis protocol in orthopaedics and traumatology.

作者信息

Unay Koray, Akan Kaya, Sener Nadir, Cakir Mustafa, Poyanli Oguz

机构信息

Orthopaedic and Traumatology Department, Goztepe Research and Training Hospital, Istanbul, Turkey.

出版信息

J Eval Clin Pract. 2009 Aug;15(4):668-74. doi: 10.1111/j.1365-2753.2008.01081.x.

Abstract

RATIONALE, AIMS AND OBJECTIVES: To evaluate the effectiveness of the deep-vein thrombosis (DVT) prophylaxis protocol for adult patients in a general orthopaedics and traumatology clinic.

METHOD

We followed the DVT prophylaxis protocol in 1326 (776 female, 550 male) of 2114 adult patients admitted to the Department of Orthopaedics and Traumatology in Goztepe Research and Training Hospital. They were followed for symptomatic DVT and possible complications of low-molecular-weight heparin (LMWH) therapy. A Doppler ultrasonography (US) was performed when DVT was suspected. The medical information treatment protocols of DVT patients were recorded.

RESULTS

Doppler US was performed in 58 patients with suspected DVT. Six of these patients were diagnosed with DVT. The side effects of LMWH were upper gastrointestinal bleeding (0.5%), widespread ecchymosis of the extremities (1.9%) and heparin-induced thrombocytopenia (0.16%).

CONCLUSION

Symptomatic DVT occurrences were similar to those in medical literature; however, there were fewer side effects of LMWH than reported in literature.

摘要

原理、目的和目标:评估综合骨科与创伤科诊所中成人患者深静脉血栓形成(DVT)预防方案的有效性。

方法

我们对戈兹特佩研究与培训医院骨科与创伤科收治的2114例成年患者中的1326例(776例女性,550例男性)采用了DVT预防方案。对这些患者进行症状性DVT及低分子肝素(LMWH)治疗可能并发症的随访。怀疑有DVT时进行多普勒超声检查(US)。记录DVT患者的医疗信息治疗方案。

结果

对58例疑似DVT患者进行了多普勒超声检查。其中6例患者被诊断为DVT。LMWH的副作用包括上消化道出血(0.5%)、四肢广泛瘀斑(1.9%)和肝素诱导的血小板减少症(0.16%)。

结论

症状性DVT的发生率与医学文献报道相似;然而,LMWH的副作用比文献报道的要少。

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