Joshi V V, Banerjee A K, Yadav K, Pathak I C
Cancer. 1977 Aug;40(2):789-95. doi: 10.1002/1097-0142(197708)40:2<789::aid-cncr2820400229>3.0.co;2-r.
Three cases of cystic partially differentiated nephroblastoma (CPDN) are presented and ten cases from literature are reviewed. CPDN has been designated by various terms; it is a cystic encapsulated tumor occurring before 2 years of age. Cysts are lined by epithelium; septa of the cysts show a mixture of partially differentiated and undifferentiated metanephrogenic blastema. This histologic feature distinguishes CPDN from multilocular cyst of kidney. In seven cases simple nephrectomy, and in remaining cases nephrectomy with radiation and/or chemotherapy, had been the treatment. The disease-free interval ranged from 5 to 72 months, without reports of recurrence or metastasis. CPDN appears to take a benign course and simple nephrectomy seems to be the treatemtn of choice. However, in view of the possibility of recurrence as shown in rare instances by congenital mesoblastic nephroma, another less aggressive lesion in the spectrum of infantile renal neoplasia, regular follow up is recommended.
本文报告了3例囊性部分分化型肾母细胞瘤（CPDN），并复习了文献中的10例。CPDN曾有多种命名；它是一种2岁前发生的囊性包膜肿瘤。囊肿内衬上皮；囊肿间隔显示部分分化和未分化的后肾胚基混合存在。这一组织学特征将CPDN与肾多房性囊肿区分开来。7例采用单纯肾切除术治疗，其余病例采用肾切除术联合放疗和/或化疗。无病生存期为5至72个月，无复发或转移报告。CPDN似乎呈良性病程，单纯肾切除术似乎是首选治疗方法。然而，鉴于先天性中胚层肾瘤（婴儿肾肿瘤谱系中的另一种侵袭性较小的病变）在罕见情况下显示有复发的可能性，建议进行定期随访。
