双相情感障碍中的性别差异：抗精神病药物剂量差异

Sex differences in bipolar affective disorder: neuroleptic dosage variance.

作者信息

D'Mello D A, McNeil J A

机构信息

Michigan State University, East Lansing.

出版信息

Compr Psychiatry. 1990 Jan-Feb;31(1):80-3. doi: 10.1016/0010-440x(90)90057-y.

DOI:10.1016/0010-440x(90)90057-y

PMID:1967568

Abstract

Bipolar affective disorder in men and women often differs in prevalence, age of onset, phenomenology, and longitudinal course. A study of 112 bipolar patients, comprising 72 women and 40 men who were discharged from an acute inpatient setting on antipsychotic drugs, is reported. Higher mean discharge neuroleptic doses were prescribed to men below the age of 40 and to women above the age of 40. The clinical implications of higher dosing patterns are discussed.

摘要

双相情感障碍在男性和女性中的患病率、发病年龄、临床表现及病程往往有所不同。本文报告了一项对112例双相情感障碍患者的研究，其中包括72名女性和40名男性，这些患者均从急性住院环境中出院，且正在服用抗精神病药物。40岁以下的男性和40岁以上的女性所开具的平均出院抗精神病药物剂量更高。文中讨论了更高剂量模式的临床意义。