Siden Harold B, Collin Kathleen
Department of Pediatrics, Children's & Women's Health Centre of British Columbia, University of British Columbia, and Canuck Place Children's Hospice.
Paediatr Child Health. 2005 Mar;10(3):163-8. doi: 10.1093/pch/10.3.163.
Clinicians are increasingly aware of the important role that opioids play in the management of a variety of paediatric conditions. Frequently, clinicians encounter challenges in initiating opioid therapy and, then, in weaning paediatric patients off opioids. In the present article, three different cases (an infant and two adolescents) are used to illustrate why and how opiates may be used in paediatrics and how they can be discontinued. The presentations include neonatal abstinence syndrome, chronic headache and cystic fibrosis. The cases are meant to emphasize the distinctions rather than the similarities among the cases, which is why this is called a case parallel, rather than a case series. The article downplays the use of rigid rules in managing patients on opioids, and emphasizes a flexible and patient-centred approach.
临床医生越来越意识到阿片类药物在多种儿科疾病管理中所起的重要作用。临床医生在开始阿片类药物治疗时，以及随后使儿科患者停用阿片类药物的过程中，经常会遇到挑战。在本文中，通过三个不同的病例（一名婴儿和两名青少年）来说明为何以及如何在儿科使用阿片类药物，以及如何停用这些药物。这些病例包括新生儿戒断综合征、慢性头痛和囊性纤维化。这些病例旨在强调各病例之间的差异而非相似之处，这就是为什么本文称为病例平行分析，而不是病例系列报道。本文不强调在管理使用阿片类药物的患者时采用严格规则，而是强调一种灵活且以患者为中心的方法。
