Department of Oral Diagnosis (Semiology), Piracicaba Dental School, State University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.
Med Oral Patol Oral Cir Bucal. 2009 Nov 1;14(11):e612-5. doi: 10.4317/medoral.14.e612.
Extra-osseous odontogenic tumors are rarely observed. However, it is widely accepted that the remains of odontogenic epithelium entrapped in the oral soft tissues may be a possible source for peripheral odontogenic tumors differentiation. Peripheral developing odontoma is considered exceptionally rare, since few similar cases are described in the English-related literature under diverse nomenclature, such as irregular eruption, ectopic tooth, ectopic soft-tissue mesiodens, ectopic odontoma and extra-osseous tooth germ. Previously reported cases invariably affected children and surgical exploration revealed tooth germs exclusively embedded in the soft tissue without bone involvement. Microscopically, all these cases exhibited developing tooth germs composed of ameloblasts, enamel matrix, odontoblastic layer, dentin and dental papilla and the morphological findings seem to depend on the developmental stage of each tooth germ at discovery. Thus, we believe that it is relevant to report two additional cases that were recently diagnosed in Brazil and Guatemala, focusing on their nomenclature, correct diagnosis and further treatment.
颌骨外的牙源性肿瘤很少见。然而，人们普遍认为，被困在口腔软组织中的牙源性上皮的残留物可能是周围牙源性肿瘤分化的一个可能来源。外周牙源性发育瘤被认为非常罕见，因为在英语相关文献中，很少有类似的病例被描述为不同的命名，如不规则萌出、异位牙、异位软组织正中牙、异位牙瘤和颌骨外牙胚。以前报道的病例无一例不影响儿童，手术探查仅发现牙胚完全嵌入软组织而无骨受累。显微镜下，所有这些病例均表现为发育中的牙胚，由成釉细胞、釉基质、成牙本质细胞层、牙本质和牙髓组成，形态学发现似乎取决于每个牙胚发现时的发育阶段。因此，我们认为有必要报告最近在巴西和危地马拉诊断的另外两例病例，重点介绍其命名、正确诊断和进一步治疗。
