RTI International, Research Triangle Park, North Carolina, USA.
Obesity (Silver Spring). 2010 Feb;18(2):333-9. doi: 10.1038/oby.2009.253. Epub 2009 Aug 13.
This study presents nationally representative estimates of individual and aggregate years-of-life-lost (YLLs) associated with overweight and three categories of obesity separately by age, race, smoking status, and gender strata. Using proportional hazards analysis and data from the National Health Interview Survey (NHIS) Linked Mortality Files, we estimated life expectancies for each BMI strata and quantified YLLs by comparing differences between each strata and the normal BMI reference group. Our results provide further evidence that overweight and mild obesity are not associated with a reduction in life expectancy. However, higher BMI categories are associated with lower expected survival. In aggregate, excess BMI is responsible for approximately 95 million YLLs. White females account for more than two-thirds of the aggregate YLLs. Unless something is done to reduce the rising prevalence of those with BMIs >35, or to mitigate the impact of obesity or its correlates on YLLs, expected life expectancy for US adults may decrease in the future.
本研究提供了具有全国代表性的估计数，分别按年龄、种族、吸烟状况和性别阶层，计算与超重和肥胖的三个类别相关的个体生命年损失（YLL）和总生命年损失。使用比例风险分析和来自国家健康访谈调查（NHIS）链接死亡率文件的数据，我们为每个 BMI 阶层估计了预期寿命，并通过比较每个阶层与正常 BMI 参考组之间的差异来量化 YLL。我们的结果进一步证明，超重和轻度肥胖与预期寿命的减少无关。然而，更高的 BMI 类别与较低的预期生存相关。总体而言，超重导致约 9500 万 YLL。白人女性占总 YLL 的三分之二以上。除非采取措施降低 BMI>35 的人群的患病率上升，或减轻肥胖或其相关因素对 YLL 的影响，否则美国成年人的预期寿命可能会在未来下降。
