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中年女性严重的更年期症状与女性和男性因素有关。

Severe menopausal symptoms in middle-aged women are associated to female and male factors.

机构信息

Academic and Research Department, Hospital Gineco-Obstétrico Enrique C. Sotomayor, Pedro Pablo Gómez s/n y 6 de Marzo, and Facultad de Ciencias Médicas, Universidad Católica de Guayaquil, Guayaquil, Ecuador.

出版信息

Arch Gynecol Obstet. 2010 May;281(5):879-85. doi: 10.1007/s00404-009-1204-z. Epub 2009 Aug 14.

Abstract

BACKGROUND

The frequency and intensity of menopausal symptoms within a given population, as assessed by several tools, may vary and depend on several factors, such as age, menopausal status, chronic conditions and personal and partner socio-demographic profile.

OBJECTIVE

To determine the frequency and intensity of menopausal symptoms and related risk factors among middle-aged women.

METHODS

In this cross-sectional study a total of 404 women aged 40 to 59 years, visiting inpatients at the Enrique C. Sotomayor Gynecology and Obstetrics Hospital, Guayaquil, Ecuador, were requested to fill out the menopause rating scale (MRS) and a questionnaire containing personal and partner data.

RESULTS

Mean age of surveyed women (n=404) was 48.2+/-5.7 years, 85.1% had 12 or less years of schooling and 44.8% were postmenopausal. None was on hormonal therapy (HT) for the menopause or psychotropic drugs. Regarding their partner, erectile dysfunction was present in 23.8%, premature ejaculation in 21.2% and 43.5% abused alcohol. The four most frequently found symptoms of those composing the MRS were muscle and joint problems (80%), depressive mood (73.5%), physical and mental exhaustion (71.3%) and irritability (68%). Mean total MRS score was 18+/-10.6 (median 17) and for subscales: 7.2+/-4.5 (somatic); 6.9+/-4.8 (psychological) and 3.9+/-3.4 (urogenital). Women presented severe scores in 53, 36.1, 48.3 and 49.8% for total MRS and somatic, psychological and urogenital subscales, respectively. After adjusting for confounding factors, logistic regression analysis determined that female higher parity and partner premature ejaculation increased the risk for presenting severe total MRS scores (impaired female quality of life), whereas women who had a positive perception of their health status were at decreased risk.

CONCLUSION

In this middle-aged series psychological menopausal symptoms were the most frequent in which severity was associated to parity and partner sexual dysfunction.

摘要

背景

在特定人群中,使用多种工具评估的更年期症状的频率和强度可能会有所不同,这取决于多种因素,如年龄、绝经状态、慢性疾病以及个人和伴侣的社会人口统计学特征。

目的

确定中年女性更年期症状的频率和强度及其相关危险因素。

方法

在这项横断面研究中,共有 404 名年龄在 40 至 59 岁之间的女性,她们在厄瓜多尔瓜亚基尔恩里克·C·索托马约尔妇科和产科医院住院,要求她们填写更年期评定量表(MRS)和一份包含个人和伴侣数据的问卷。

结果

接受调查的女性(n=404)的平均年龄为 48.2+/-5.7 岁,85.1%接受过 12 年或以下的学校教育,44.8%处于绝经后状态。没有人因更年期接受激素治疗(HT)或精神药物治疗。关于她们的伴侣,23.8%存在勃起功能障碍,21.2%存在早泄,43.5%存在酗酒问题。MRS 组成部分中最常见的四种症状是肌肉和关节问题(80%)、抑郁情绪(73.5%)、身心疲惫(71.3%)和易怒(68%)。MRS 总评分的平均得分为 18+/-10.6(中位数为 17),亚量表评分为:7.2+/-4.5(躯体);6.9+/-4.8(心理)和 3.9+/-3.4(泌尿生殖)。在总 MRS 及躯体、心理和泌尿生殖亚量表中,女性严重评分分别为 53%、36.1%、48.3%和 49.8%。在校正混杂因素后,逻辑回归分析确定,女性较高的生育次数和伴侣早泄增加了出现严重总 MRS 评分(女性生活质量受损)的风险,而对自身健康状况有积极认知的女性风险降低。

结论

在这个中年人群中,最常见的是心理更年期症状,严重程度与生育次数和伴侣性功能障碍有关。

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