Ferrari Marco, Cagidiaco Maria Crysanti, Monticelli Francesca, Kugel Gerard, Barker Matthew L, Gerlach Robert W
Research Center for Dentistry, Piazza Attias, 19, 57125 Livorno, Italy.
Am J Dent. 2007 Sep;20 Spec No A:19A-22A.
To compare the clinical response of 6% hydrogen peroxide whitening strips and a 10% carbamide peroxide custom tray system under common daytime usage conditions, in an Italian dental research center.
Informed consent and baseline measurements were collected, and 43 healthy adults were randomly assigned to 6% hydrogen peroxide whitening strips (Crest Whitestrips) or the 10% carbamide peroxide custom tray (Opalescence 10%). The maxillary arch was treated twice daily for 30 minutes at-home. Treatment was discontinued after 2 weeks, and subjects were monitored for an additional 4 weeks. Efficacy (initial and sustained) was measured objectively from standard digital images of the maxillary facial tooth surfaces using the international CIELAB system. Safety was assessed from interview and examination. Treatments were compared after 2 weeks (end-of-treatment) and 6 weeks (4 weeks post-treatment) using analysis of covariance methods.
Both groups exhibited color improvement at the Week 2 end-of-treatment visit. For yellowness, mean (SD) Deltab* at Week 2 was -2.10 (0.70) for the strip group and -1.61 (1.03) for the tray group. For lightness, mean (SD) DeltaL* at Week 2 was 1.25 (0.92) for the strip group and 1.17 (1.19) for the tray group. Compared to Week 2, the strip group retained 89-92% of the initial Deltab* and DeltaL* color improvement at Week 6 (4 weeks post-treatment), while the tray group had 80-90%. Groups differed significantly (P< 0.05) on end-of-treatment and post-treatment Deltab*, favoring the strips. Both daytime treatments were well-tolerated, with minor tooth sensitivity and oral irritation representing the most common findings.
在意大利一家牙科研究中心，比较6%过氧化氢美白牙贴和10%过氧化脲定制托盘系统在日常白天使用条件下的临床反应。
收集知情同意书和基线测量数据，43名健康成年人被随机分配到6%过氧化氢美白牙贴（佳洁士美白牙贴）组或10%过氧化脲定制托盘（欧帕丽尔10%）组。上牙弓在家中每天治疗两次，每次30分钟。2周后停止治疗，对受试者再监测4周。使用国际CIELAB系统从标准的上颌面部牙齿表面数字图像中客观测量疗效（初始和持续）。通过访谈和检查评估安全性。使用协方差分析方法在2周（治疗结束时）和6周（治疗后4周）对治疗效果进行比较。
两组在治疗第2周结束时均表现出颜色改善。对于黄度，牙贴组在第2周时平均（标准差）Δb为-2.10（0.70），托盘组为-1.61（1.03）。对于明度，牙贴组在第2周时平均（标准差）ΔL为1.25（0.92），托盘组为1.17（1.19）。与第2周相比，牙贴组在第6周（治疗后4周）保留了初始Δb和ΔL颜色改善的89 - 92%，而托盘组为80 - 90%。两组在治疗结束时和治疗后Δb*方面存在显著差异（P < 0.05），牙贴组更优。两种白天治疗方法耐受性良好，最常见的情况是轻微牙齿敏感和口腔刺激。
