Department of Physiology, Xiamen Medical College, Xiamen University, Xiamen City, Fujian Province, People's Republic of China.
Physiol Res. 2010;59(3):323-329. doi: 10.33549/physiolres.931734. Epub 2009 Aug 12.
Intracellular free Ca2+ is one of important biological signals regulating a number of cell functions. It has been discussed widely and extensively in several cell types during the past two decades. Attention has been paid to the Ca2+ transportation in mesenchymal stem cells in recent years as mesenchymal stem cells have gained considerable interest due to their potential for cell replacement therapy and tissue engineering. In this paper, roles of intracellular Ca2+ oscillations and its transporters in mesenchymal stem cells have been reviewed.
细胞内游离 Ca2+ 是调节许多细胞功能的重要生物信号之一。在过去的二十年中，已经在几种细胞类型中广泛讨论了 Ca2+。近年来，由于间充质干细胞具有细胞替代治疗和组织工程的潜力，因此人们对间充质干细胞中的 Ca2+ 转运越来越关注。本文综述了细胞内 Ca2+ 振荡及其转运在间充质干细胞中的作用。
