Erne Jay B, Goring Robert L, Kennedy Fidelma A, Schoenborn William C
Affiliated Veterinary Specialists, 275 Corporate Way, Ste 100, Orange Park, FL 32073, USA.
J Am Vet Med Assoc. 2009 Aug 15;235(4):386-90. doi: 10.2460/javma.235.4.386.
To determine the prevalence of lymphoplasmacytic synovitis (LPS) in dogs with naturally occurring cranial cruciate ligament (CCL) rupture and compare clinical, radiographic, cytologic, and histologic findings in dogs with and without LPS.
Cross-sectional study.
110 dogs with naturally occurring CCL rupture.
Histologic examination of synovial biopsy specimens obtained at the time of surgical treatment was used to identify dogs with LPS. Clinical, radiographic, cytologic, and histologic findings were compared between dogs with and without LPS.
56 (51%) dogs had histologic evidence of LPS. There were no significant differences in age, body weight, duration of lameness, severity of lameness, severity of radiographic signs of degenerative joint disease, extent of CCL rupture (partial vs complete), or gross appearance of the medial meniscus between dogs with and without LPS. Mean tibial plateau angle was significantly lower in dogs with LPS than in dogs without LPS, and dogs with LPS were significantly more likely to have neutrophils in their synovial fluid. Lymphocytes were seen in synovial fluid from a single dog with LPS.
Results suggested that LPS was common in dogs with naturally occurring CCL rupture. However, only minor clinical, radiographic, cytologic, and histologic differences were identified between dogs with and without LPS.
确定自然发生颅交叉韧带（CCL）断裂的犬中淋巴浆细胞性滑膜炎（LPS）的患病率，并比较有和没有LPS的犬的临床、放射学、细胞学和组织学检查结果。
横断面研究。
110只自然发生CCL断裂的犬。
手术治疗时获取的滑膜活检标本的组织学检查用于识别患有LPS的犬。比较有和没有LPS的犬的临床、放射学、细胞学和组织学检查结果。
56只（51%）犬有LPS的组织学证据。有和没有LPS的犬在年龄、体重、跛行持续时间、跛行严重程度、退行性关节病的放射学征象严重程度、CCL断裂程度（部分断裂与完全断裂）或内侧半月板大体外观方面没有显著差异。LPS犬的平均胫骨平台角显著低于无LPS犬，且LPS犬的滑液中更有可能出现中性粒细胞。在一只患有LPS的犬的滑液中发现了淋巴细胞。
结果表明，LPS在自然发生CCL断裂的犬中很常见。然而，有和没有LPS的犬之间仅发现了轻微的临床、放射学、细胞学和组织学差异。
