韩国临床分离株中 bla(CMY-10)基因与携带 ISCR1 元件的新型复合类 1 整合子的关联。
Association of the bla(CMY-10) gene with a novel complex class 1 integron carrying an ISCR1 element in clinical isolates from Korea.
机构信息
Department of Biological Sciences, Drug Resistance Proteomics Laboratory, Myongji University, Yongin, Gyeonggido, Korea.
出版信息
Clin Microbiol Infect. 2010 Jul;16(7):1013-7. doi: 10.1111/j.1469-0691.2009.03002.x. Epub 2009 Jul 21.
Abstract
The bla(CMY-10) gene responsible for β-lactam resistance was located on a new complex class 1 integron within a conjugative plasmid. The sul1-type class 1 integron, containing an aadA2a gene cassette, was identified upstream of bla(CMY-10). A unique gene array (yqgF-yqgE-gshB-orf97--orf105) was identified downstream of bla(CMY-10.).
摘要
负责β-内酰胺类药物耐药的 bla(CMY-10)基因位于一个新的复杂的 1 类整合子内，该整合子位于一个可接合性质粒上。在 bla(CMY-10)的上游发现了一个包含 aadA2a 基因盒的 sul1 型 1 类整合子。在 bla(CMY-10)的下游发现了一个独特的基因簇(yqgF-yqgE-gshB-orf97--orf105)。
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