Bae Il Kwon, Lee You-Nae, Lee Wee Gyo, Lee Sang Hee, Jeong Seok Hoon
Research Institute for Antimicrobial Resistance and Department of Laboratory Medicine, Kosin University College of Medicine, 34 Amnam-Dong, Suh-Gu, Busan, Republic of Korea.
Antimicrob Agents Chemother. 2007 Aug;51(8):3017-9. doi: 10.1128/AAC.00279-07. Epub 2007 May 21.
This work identifies an ISCR1-related bla(CTX-M-14) gene, which has never been reported before, from a clinical isolate of Escherichia coli. The bla(CTX-M-14) gene was preceded by an ISCR1 element that was followed by a class 1 integron containing three different insert gene cassettes, i.e., dfrA12, orfF, and aadA2.
这项研究从一株临床分离的大肠杆菌中鉴定出一个此前从未报道过的与ISCR1相关的bla(CTX-M-14)基因。bla(CTX-M-14)基因之前是一个ISCR1元件,其后是一个1类整合子,该整合子包含三个不同的插入基因盒,即dfrA12、orfF和aadA2。