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糖尿病成年患者认知功能和社会支持与血糖控制之间的关联

Association between cognitive function and social support with glycemic control in adults with diabetes mellitus.

作者信息

Okura Toru, Heisler Michele, Langa Kenneth M

机构信息

Divisions of Geriatric Medicine, Department of Internal Medicine, University of Michigan at Ann Arbor, Michigan Department of Veterans Affairs, Ann Arbor, Michigan, USA.

出版信息

J Am Geriatr Soc. 2009 Oct;57(10):1816-24. doi: 10.1111/j.1532-5415.2009.02431.x. Epub 2009 Aug 13.

Abstract

OBJECTIVES

To examine whether cognitive impairment in adults with diabetes mellitus is associated with worse glycemic control and to assess whether level of social support for diabetes mellitus care modifies this relationship.

DESIGN

Cross-sectional analysis.

SETTING

The 2003 Health and Retirement Study (HRS) Mail Survey on Diabetes and the 2004 wave of the HRS.

PARTICIPANTS

Adults aged 50 and older with diabetes mellitus in the United States (N=1,097, mean age 69.2).

MEASUREMENTS

Glycosylated hemoglobin (HbA1c) level; cognitive function, measured with the 35-point HRS cognitive scale (HRS-cog); sociodemographic variables; duration of diabetes mellitus; depressed mood; social support for diabetes mellitus care; self-reported knowledge of diabetes mellitus; treatments for diabetes mellitus; components of the Total Illness Burden Index related to diabetes mellitus; and functional limitations.

RESULTS

In an ordered logistic regression model for the three ordinal levels of HbA1c (<7.0, 7.0-7.9, >or=8.0 mg/dL), respondents with HRS-cog scores in the lowest quartile had significantly higher HbA1c levels than those in the highest cognitive quartile (adjusted odds ratio=1.80, 95% confidence interval=1.11-2.92). A high level of social support for diabetes mellitus care modified this association; for respondents in the lowest cognitive quartile, those with high levels of support had significantly lower odds of having higher HbA1c than those with low levels of support (1.11 vs 2.87, P=.02).

CONCLUSION

Although cognitive impairment was associated with worse glycemic control, higher levels of social support for diabetes mellitus care ameliorated this negative relationship. Identifying the level of social support available to cognitively impaired adults with diabetes mellitus may help to target interventions for better glycemic control.

摘要

目的

研究成年糖尿病患者的认知障碍是否与血糖控制较差有关,并评估糖尿病护理的社会支持水平是否会改变这种关系。

设计

横断面分析。

背景

2003年健康与退休研究(HRS)糖尿病邮件调查以及2004年HRS调查。

参与者

美国50岁及以上的成年糖尿病患者(N = 1097,平均年龄69.2岁)。

测量指标

糖化血红蛋白(HbA1c)水平;认知功能,采用35分的HRS认知量表(HRS-cog)测量;社会人口统计学变量;糖尿病病程;抑郁情绪;糖尿病护理的社会支持;自我报告的糖尿病知识;糖尿病治疗;与糖尿病相关的总疾病负担指数的组成部分;以及功能限制。

结果

在HbA1c的三个有序水平(<7.0、7.0 - 7.9、≥8.0 mg/dL)的有序逻辑回归模型中,HRS-cog得分处于最低四分位数的受访者的HbA1c水平显著高于认知水平最高四分位数的受访者(调整后的优势比 = 1.80,95%置信区间 = 1.11 - 2.92)。高水平的糖尿病护理社会支持改变了这种关联;对于认知水平最低四分位数的受访者,获得高支持水平的人HbA1c升高的几率显著低于低支持水平的人(1.11对2.87,P = 0.02)。

结论

虽然认知障碍与较差的血糖控制有关,但较高水平的糖尿病护理社会支持改善了这种负面关系。确定认知障碍成年糖尿病患者可获得的社会支持水平可能有助于针对更好的血糖控制进行干预。

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