Clinical Medical College of Chengdu Medical College, First Affiliated Hospital, Chengdu, China.
The Fourth Hospital of West China, Sichuan University, Chengdu, China.
Front Endocrinol (Lausanne). 2024 Aug 20;15:1390564. doi: 10.3389/fendo.2024.1390564. eCollection 2024.
The aim of this research was to ascertain the correlations between alexithymia, social support, depression, and glycemic control in patients diagnosed with type 2 diabetes mellitus. Additionally, this study sought to delve into the potential mediating effects of social support and depression in the relationship between alexithymia and glycemic control.
A purposive sampling methodology was employed to select a cohort of 318 patients afflicted with type 2 diabetes mellitus, hailing from a care establishment situated in Chengdu City. This investigation embraced a cross-sectional framework, wherein instruments such as the General Information Questionnaire, the Toronto Alexithymia Scale 20, the Social Support Rating Scale, and the Hamilton Depression Scale were judiciously administered. The primary objective of this endeavor was to unravel the interplay that exists amongst alexithymia, social support, depression, and glycemic control. The inquiry discerned these interrelationships through both univariate and correlational analyses, subsequently delving into a comprehensive exploration of the mediating ramifications engendered by social support and depression in the nexus between alexithymia and glycemic control.
The HbA level of patients diagnosed with type 2 diabetes mellitus was recorded as (8.85 ± 2.107), and their current status with regards to alexithymia, social support, and depression were measured as (58.05 ± 4.382), (34.29 ± 4.420), and (7.17 ± 3.367), respectively. Significant correlations were found between HbA and alexithymia (R=0.392, <0.01), social support (R=-0.338, <0.01), and depression (R=0.509, <0.01). Moreover, alexithymia correlation with social support (R=-0.357, <0.01) and with depression (R=0.345, <0.01). Regarding the mediation analysis, the direct effect of alexithymia on HbA was calculated to be 0.158, while the indirect effect through social support and depression were 0.086 and 0.149, respectively. The total effect value was determined to be 0.382, with the mediating effect accounting for 59.95%, and the direct effect accounting for 40.31%.
Alexithymia exerts both direct and indirect adverse effects on glycemic control, thereby exacerbating disease outcomes. Hence, it is imperative to prioritize the mental health status of individuals with type 2 diabetes to enhance overall well-being, ameliorate diabetes-related outcomes, elevate patients' quality of life, and alleviate the psychological distress and financial burden associated with the condition.
本研究旨在确定 2 型糖尿病患者的述情障碍、社会支持、抑郁与血糖控制之间的相关性。此外,本研究还探讨了社会支持和抑郁在述情障碍与血糖控制之间的关系中的潜在中介作用。
采用目的抽样法选取 318 名来自成都市某护理机构的 2 型糖尿病患者作为研究对象。本研究采用横断面设计,使用一般信息问卷、多伦多述情障碍量表 20 版、社会支持评定量表和汉密尔顿抑郁量表等工具进行评估。本研究的主要目的是揭示述情障碍、社会支持、抑郁与血糖控制之间的相互关系。研究通过单变量和相关分析来识别这些关系,然后深入探讨社会支持和抑郁在述情障碍和血糖控制之间的中介作用。
2 型糖尿病患者的 HbA1c 水平为(8.85±2.107),其述情障碍、社会支持和抑郁的现状分别为(58.05±4.382)、(34.29±4.420)和(7.17±3.367)。HbA1c 与述情障碍(R=0.392,<0.01)、社会支持(R=-0.338,<0.01)和抑郁(R=0.509,<0.01)呈显著正相关。此外,述情障碍与社会支持(R=-0.357,<0.01)和抑郁(R=0.345,<0.01)呈显著正相关。关于中介分析,述情障碍对 HbA1c 的直接效应为 0.158,通过社会支持和抑郁的间接效应分别为 0.086 和 0.149。总效应值为 0.382,中介效应占 59.95%,直接效应占 40.31%。
述情障碍对血糖控制既有直接影响,也有间接影响,从而加重疾病结局。因此,优先考虑 2 型糖尿病患者的心理健康状况对于提高整体幸福感、改善糖尿病相关结局、提高患者生活质量以及减轻与疾病相关的心理困扰和经济负担至关重要。