Yan Hede, Zhang Feng, Chen Michael B, Lineaweaver William C
Division of Plastic Surgery, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Int Rev Neurobiol. 2009;87:199-225. doi: 10.1016/S0074-7742(09)87010-4.
The use of nerve conduits as an alternative for nerve grafting has a long experimental and clinical history. Luminal additives, factors introduced into these nerve conduits, were later developed to enhance the nerve regeneration through conduits. This chapter generalizes the types of additives used, and the reported performance of luminal additives in conduits to present a preference list for the most effective additives to use over specific distances of nerve defect.
