Terenghi Giorgio, Wiberg Mikael, Kingham Paul J
Blond McIndoe Laboratories, Tissue Injury and Repair Group, School of Medicine, University of Manchester, Manchester, United Kingdom.
Int Rev Neurobiol. 2009;87:393-403. doi: 10.1016/S0074-7742(09)87021-9.
A clear need exists for new surgical approaches to enhance the recuperation of functions after peripheral nerve injury and repair. At present, advances in the regenerative medicine fields of biomaterials, cellular engineering, and molecular biology are all contributing to the development of a bioengineered nerve implant, which could be used clinically as an alternative to nerve autograft. In this review we examine the recent progress in this field, looking in particular at the applicability of Schwann cells and stem cell transplantation to enhance nerve regeneration.
显然需要新的手术方法来促进周围神经损伤和修复后的功能恢复。目前，生物材料、细胞工程和分子生物学等再生医学领域的进展都在推动生物工程神经植入物的开发，这种植入物可在临床上用作神经自体移植的替代物。在这篇综述中，我们研究了该领域的最新进展，特别关注雪旺细胞和干细胞移植在促进神经再生方面的适用性。
