Arya Rajiv, Hansen Allison, Taira Breena R, Packy Theodore, Singer Adam J
Department of Emergency Medicine, Stony Brook University Medical Center, Stony Brook, NY 11794-8350, USA.
Am J Emerg Med. 2009 Sep;27(7):847-50. doi: 10.1016/j.ajem.2008.06.015.
The aim of this study was to compare the taste of computed tomography (CT) oral contrast diluted with various flavored drinks.
We performed a prospective, blinded, controlled trial in healthy adult volunteers. Subjects were assigned to ingest four 250-mL aliquots of oral contrast media diluted in water, Crystal Light Lemonade (Kraft Food, Northfield, Ill), Tropical Punch Kool-Aid (Kraft Food), and Tropicana orange juice (Pepsi Bottling Company, Sommers, NY) in random order; and the taste of the solution was measured with a 100-mm visual analogue scale and 5-point Likert scale from very worst to best. Between-group comparison of the taste scores was performed with repeated-measures analysis of variance and pairwise t tests. The study had 80% power to detect an effect size 0.75 SDs.
There were 23 subjects; mean (SD) age was 33 (7.7) and 30% were female. The mean (SD) taste scores were water 12 (5), lemonade 37 (21), Kool-Aid 44 (20), and orange juice 40 (20) (P < .05). The proportion of subjects completely ingesting the contrast in water (65%) was significantly less than that with other 3 study solutions (100% each, P < .001).
Dilution of oral contrast media with lemonade, fruit punch, or orange juice is tastier than with water. The choice of the specific juice used to dilute the oral contrast should be individualized based on patient preferences and availability.
本研究旨在比较用各种调味饮料稀释的计算机断层扫描(CT)口服造影剂的味道。
我们在健康成年志愿者中进行了一项前瞻性、双盲、对照试验。受试者被随机分配按顺序摄入四份250毫升用以下液体稀释的口服造影剂:水、水晶轻柠檬水(卡夫食品公司,伊利诺伊州诺斯菲尔德)、热带潘趣果汁饮料(卡夫食品公司)和纯果乐橙汁(百事瓶装公司,纽约州萨默斯);并用100毫米视觉模拟量表和从非常差到最好的5点李克特量表测量溶液的味道。采用重复测量方差分析和两两t检验对组间味道评分进行比较。该研究有80%的把握度检测到效应大小为0.75标准差。
共有23名受试者;平均(标准差)年龄为33岁(7.7岁),30%为女性。平均(标准差)味道评分分别为:水12(5)、柠檬水37(21)、果汁饮料44(20)和橙汁40(20)(P < 0.05)。完全摄入用水稀释的造影剂的受试者比例(65%)显著低于其他三种研究溶液(均为100%,P < 0.001)。
用柠檬水、果汁饮料或橙汁稀释口服造影剂比用水更美味。用于稀释口服造影剂的特定果汁的选择应根据患者的偏好和可用性进行个体化。